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Pharmaceutical Aerosols Hfa-134A Medication,Pharmaceutical Aerosols Hfa-134A Medication
Pharmaceutical product HFA-134A (P) obtained in 2016 the DMF file number in USA
HFA-134 Chemical Name: Pharmaceutical Excipients Tetrafuoroethane
Pharmaceutical aerosols containing HFA-134a are used to deliver medication directly into the lungs. HFA-134a is a propellant used in the aerosol spray to help deliver the medication in the form of small particles. This type of delivery method is commonly used for medications used to treat asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions.
Some common medications delivered through HFA-134a aerosols include albuterol, beclomethasone, fluticasone, and ipratropium. These medications work by opening up the airways and reducing inflammation in the lungs, allowing the patient to breathe more easily.
HFA-134a aerosols are preferred over older propellants, such as chlorofluorocarbons (CFCs), due to their lower impact on the environment and ozone layer. Additionally, HFA-134a is less likely to cause irritation to the lungs and throat, making it a safer and more comfortable option for patients.
The Relative Name: Aerosol Medication, Propellant Hfa-134a, Prokinetic Agents, Propellant R134a, Aerosol Inhaler, Inhalation Aerosol, Hfa Inhaler
Cas No.: 711-97-2
Molecular Formula: CH2FCF3
Physical Properties:
Molecular weight(g/mol): 102.3
Melting point℃: -103.15℃
r134a boiling point: -26.1℃
Density of liquid (25℃ ): 1.207 g/cm3
Vapour pressure(25℃): 0.665MPa
Critical temperature (℃): 101.1
Critical pressure: 4.067 MPa
R134a Density: 1.206g/cm3
Latent heat of evaporation in boiling point: 215.0KJ/kg
Solubility in water (25℃): 0.15 W%
Specific heat (25℃ liquid): 1.51 KJ/kg . k
ODP: 0
GWP(100yr): 1200
|
Packing Specifications: |
Disposable cylinder:30lb/13.6kg, (25lb/11.3kg; 24lb/10.9kg) ISO-TANK OEM is acceptable |
Technical Specifications:
|
Item |
Index |
results |
|
properities |
colorless gas, slight ether smell, odorless, liquid |
pass |
|
identification(1) |
rared spectrum meets requirem |
pass |
|
Identification(2) |
retention time of test gas's main peak is consist with that of reference gas's main peak |
pass |
|
purity of 1,1,1,2-tetrafluorethane,ω/% ≥ |
99.99 |
99.99 |
|
moisture,ω/% ≤ |
0.0010 |
0.0004 |
|
acidity(as HCL),ω/% ≤ |
0.00001 |
not detected |
|
high boiling residue,ω/% ≤ |
0.0005 |
0.0004 |
|
chloride(detection limit 0.0003%) |
no muddy |
pass |
|
non-condensable gas in gas phrase(25°C)/%(v/v) |
1.5 |
0.5 |
********************THE SAMPLE COULD BE PREPARED ON CUSTOMER'S REQUEST*******************
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