High-Purity Norflurane HFA-134a Propellant for Pharmaceutical Aerosols
Pharmaceutical HFA-134a propellant (Norflurane) is a high-purity hydrofluoroalkane widely used as a propellant for pressurized metered dose inhalers (pMDI) and other medicinal aerosol delivery systems.
As a professional HFA-134a pharmaceutical propellant supplier, we provide bulk pharmaceutical aerosol propellant sourcing solutions for global pharmaceutical manufacturers, contract manufacturers, and medical aerosol producers.
Our Norflurane HFA-134a pharma grade propellant is manufactured under strict quality control to ensure consistent vapor pressure, chemical stability, and drug compatibility, meeting the demanding requirements of inhalation drug delivery systems.
Why Choose Our Pharmaceutical HFA-134a Propellant Supply
For B2B procurement teams evaluating medical propellant HFA-134a wholesale partners, supply stability and regulatory compliance are critical. Our offering is designed specifically for industrial and pharmaceutical purchasing requirements.
Reliable Bulk Supply for Pharmaceutical Manufacturers
Continuous production capacity for bulk pharmaceutical aerosol propellant
Global logistics support for regulated chemical transportation
Flexible packaging for different filling systems
Stable long-term supply contracts available
Pharmaceutical-Grade Purity and Compliance
High purity Norflurane suitable for inhalation formulations
Manufactured under controlled quality systems
Batch traceability and documentation support
Technical documentation available for regulatory submissions
Optimized for pMDI Performance
Consistent spray characteristics
Excellent compatibility with active pharmaceutical ingredients
Non-flammable and chemically stable propellant
Suitable for precision dosing aerosol systems
What is pMDI? How it works?
Pressurized metered dose inhaler (pMDI), also known as a puffer, is the most commonly used delivery device and is most effective when used with a spacer. The canister of a metered dose inhaler contains the medication in a solution or suspension. This pressurised canister is also filled with propellant norflurane HFA 134a, that do not react with the medication. When the canister is activated by pressing on the top of it when it is attached to the mouthpiece, a small amount of this gas is released and takes some of the medication with it. This vapour of air and medication is then channelled through the mouthpiece and delivered to the lungs when the patient inhales. Metered dose inhalers are designed so that each usage delivers a precise amount of medication. A dose counter may be included to indicate the number of doses that has been taken.
Applications of Norflurane HFA-134a in Pharmaceutical Manufacturing
Our HFA 134a propellant for pMDI manufacturer use is widely applied in the following pharmaceutical production scenarios:
Pharmaceutical Aerosol Drug Delivery
Pressurized metered dose inhalers (pMDIs)
Respiratory therapy inhalation systems
Topical medicinal aerosols
Controlled-dose pharmaceutical sprays
Industrial Pharmaceutical Production
Contract manufacturing organizations (CMOs)
Generic inhaler production
Aerosol formulation development
Pilot scale to commercial scale production
This makes our product ideal for buyers searching for:
✔ pharmaceutical aerosol propellant bulk supply
✔ HFA-134a propellant sourcing for inhaler production
✔ pharma grade Norflurane supplier
✔ medical aerosol propellant manufacturer
Environmental Impact comparison
| Parameter | HFA 134a | CFC-11 | CFC-12 |
|---|---|---|---|
| ODP | 0 | 1 | 1 |
| GWP (100-yr) | 1430 | 4660 | 10200 |
| Atmospheric Lifetime | 14 yrs | 45 yrs | 100 yrs |
Technical Specifications of Pharmaceutical Norflurane HFA-134a
Below is the structured technical specification format optimized for procurement evaluation and search engine indexing.
|
tem |
Index |
results |
|
properities |
colorless gas, slight ether smell, odorless, liquid |
pass |
|
identification(1) |
rared spectrum meets requirem |
pass |
|
Identification(2) |
retention time of test gas's main peak is consist with that of reference gas's main peak |
pass |
|
purity of 1,1,1,2-tetrafluorethane,ω/% ≥ |
99.99 |
99.99 |
|
moisture,ω/% ≤ |
0.0010 |
0.0004 |
|
acidity(as HCL),ω/% ≤ |
0.00001 |
not detected |
|
high boiling residue,ω/% ≤ |
0.0005 |
0.0004 |
|
chloride(detection limit 0.0003%) |
no muddy |
pass |
|
non-condensable gas in gas phrase(25°C)/%(v/v) |
1.5 |
0.5 |
aerosol propellant HFA 134A common Packing
30lb/13.6kg Disposable cylinder
926L Ton Cylinder
22 Ton ISOTANK
Supply Capability for Global B2B Procurement
As a professional Norflurane HFA-134a bulk supplier, we support international pharmaceutical manufacturers with:
Stable production capacity
Export documentation support
Regulatory information package
Long-term procurement cooperation
Technical consultation for formulation compatibility
We understand the decision factors of pharmaceutical procurement teams, including supply continuity, specification consistency, and delivery reliability.
Frequently Asked Questions for Procurement Teams
Q1: What distinguishes pharmaceutical-grade Norflurane HFA‑134a from industrial HFA‑134a?
"Pharmaceutical-grade Norflurane HFA‑134a undergoes stringent purification processes to remove moisture, hydrocarbons, and non-volatile residues, ensuring compliance with FDA and EMA standards. This level of purity is essential for maintaining precise dosing and aerosol stability in inhalers, whereas industrial-grade HFA‑134a is not suitable for medical applications."
Q2: How does HFA‑134a propellant impact inhaler performance?
"The stability and consistency of Norflurane HFA‑134a directly influence particle size distribution, spray uniformity, and valve reliability in metered-dose inhalers. By using pharmaceutical-grade propellant, manufacturers ensure accurate dosing and patient safety across multiple actuations."
Q3: What documentation accompanies Norflurane HFA‑134a shipments?
"Each batch comes with a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and compliance documentation. These support regulatory audits and quality control reviews, giving procurement teams confidence in both safety and traceability."
Q4: How should Norflurane HFA‑134a be stored and handled?
"Store cylinders in a cool, dry, and well-ventilated area, away from heat or ignition sources. Maintain cylinder integrity during transport to preserve purity and pressure. Proper handling ensures the propellant maintains optimal performance for medical applications."
hFA134a propellant supplier Tel：+86-592-5803997
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✔ pharmaceutical HFA-134a propellant supplier
✔ Norflurane pharma grade propellant sourcing
✔ HFA-134a bulk procurement for inhaler production
✔ medical aerosol propellant wholesale
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