As a leading global supplier of pharmaceutical-grade Norflurane HFA 134a, we specialize in providing high-purity propellant solutions for aerosol in pharmacy, aerosol industrial pharmacy, and aerosol pharma applications. Our HFA 134a is the propellant of choice for manufacture of pharmaceutical aerosols, ensuring optimal performance in medicinal aerosols for respiratory therapies, topical sprays, and nasal drug delivery.
This article explores why Norflurane HFA 134a remains the gold standard in pharmaceutical aerosols, its key benefits, and how our high-quality propellant supports global healthcare needs.
Why Choose Norflurane HFA 134a for Pharmaceutical Aerosols?
1. Superior Drug Delivery Performance
Consistent Particle Size (1-5 µm): Ensures deep lung penetration for respiratory aerosols (asthma, COPD inhalers).
Stable Suspension Properties: Maintains uniform drug dispersion in medicinal aerosols.
Precise Metered Dosing: Critical for aerosol pharma applications requiring exact dosage control.
2. Regulatory Compliance & Safety
Pharmaceutical-Grade Purity (≥99.97%): Meets USP, EP, and JP standards for manufacture of pharmaceutical aerosols.
Non-Toxic & Non-Flammable: Safe for use in aerosol industrial pharmacy applications.
CFC-Free & Ozone-Safe: Compliant with Montreal Protocol regulations.
3. Environmental & Manufacturing Advantages
Lower GWP than CFCs: While still under review, HFA 134a remains essential for transitional sustainability.
Compatible with Modern Filling Systems: Supports high-efficiency aerosol production lines.
Global Supply Chain Reliability: We ensure consistent availability for pharmaceutical aerosol manufacturers.
Applications of Norflurane HFA 134a in Pharma
1. Respiratory Inhalers (pMDIs)
Asthma & COPD Treatments: Albuterol, corticosteroids, and combination therapies.
Vaccine & Biologic Delivery: Emerging applications in pulmonary drug delivery.
2. Topical & Nasal Sprays
Antiseptic & Wound Care Sprays
Nasal Decongestants & Steroid Sprays
3. Emerging Pharma Aerosol Technologies
Smart Inhalers (IoT-Enabled Devices)
Needle-Free Vaccine Delivery Systems
Technical Specifications of hFA 134a propellant
Physicochemical Properties
| Property | Specification |
|---|---|
| Chemical Name | 1,1,1,2-Tetrafluoroethane |
| Molecular Formula | CF₃CH₂F |
| Molecular Weight | 102.03 g/mol |
| Boiling Point | -26.3°C (-15.3°F) |
| Vapor Pressure | 5.7 bar at 20°C |
| Density (liquid, 25°C) | 1.21 g/cm³ |
| Ozone Depletion Potential (ODP) | 0 |
| Global Warming Potential (GWP) | 1430 |
Purity Specifications
Performance Characteristics
Particle size distribution: 1-5 μm (ideal for pulmonary delivery)
Dose uniformity: ≤5% variation between actuations
Temperature stability: 15-30°C operating range
Comparison with Alternative Propellants
| Parameter | HFA 134a | HFA 152a | HFA 227ea | HFO-1234ze |
|---|---|---|---|---|
| ODP | 0 | 0 | 0 | 0 |
| GWP | 1430 | 138 | 3220 | <1 |
| Boiling Point (°C) | -26.3 | -24.7 | -16.4 | -19 |
| Vapor Pressure (bar, 20°C) | 5.7 | 4.16 | 3.9 | 4.2 |
Our Commitment to Quality & Sustainability
As a trusted supplier of Norflurane HFA 134a, we ensure:
✔ High-Purity Pharmaceutical Grade (meets global pharmacopeia standards)
✔ Strict Quality Control (batch testing for impurities, moisture, and stability)
✔ Sustainable Sourcing & Logistics (minimizing carbon footprint)
✔ Technical Support for Aerosol Manufacturers (formulation optimization, regulatory guidance)
Partner with a Trusted HFA 134a propellant Supplier
Norflurane HFA 134a remains the most reliable propellant for aerosol in pharmacy, offering unmatched performance in medicinal aerosols and aerosol industrial pharmacy applications.
As regulations evolve and next-generation propellants emerge, we continue to provide high-quality HFA 134a while supporting sustainable innovation in aerosol pharma.
Contact us today to discuss your pharmaceutical aerosol propellant needs and ensure your formulations meet the highest industry standards.
Our address
Room 1102, Unit C, Xinjing Center, No.25 Jiahe Road, Siming District, Xiamen, Fujan, China
Phone Number
+86-592-5803997
susan@xmjuda.com
