What is HFE Hydrofluoroether?
HFE (Hydrofluoroether) is a class of organic compounds composed of hydrogen, fluorine, carbon and oxygen, combining ether bonds (R-O-R') and fluoroalkyl structures. It is designed to retain the excellent performance of fluorinated solvents while reducing environmental impacts (such as ozone layer depletion and global warming potential). HFE is widely used as a precision cleaning agent, coolant, solvent carrier, etc., especially in the electronics, semiconductor and aerospace fields.
Main characteristics of HFE Hydrofluoroether
1.Chemical stability
Heat-resistant, hydrolysis-resistant, not easy to react with acids, alkalis or oxidants, suitable for precision instrument cleaning.
Low surface tension, can quickly penetrate tiny gaps.
2.Environmental friendliness
ODP (ozone depletion potential) ≈ 0, does not contain chlorine or bromine, does not damage the ozone layer.
GWP (global warming potential) is low, and the GWP of some HFEs is significantly lower than that of traditional PFCs (perfluorinated compounds).
3.Physical properties
Wide boiling point range (30°C~160°C), different models can be selected according to needs.
Non-flammable or difficult to burn, high safety (no flash point or high flash point).
Excellent insulation performance, suitable for electronic equipment cleaning.
4.Low toxicity
Low skin irritation, low volatile organic compound (VOC) content, but still needs to be used in a ventilated environment.
Common HFE models and uses
| Model | Chemical Name | Major production companies | Application Scenario |
| HFE-7100 | Methyl Nonafluorobutyl Ether | 3M, Solvay | Precision cleaning (semiconductors, optical components), desiccants, electronic cooling |
| HFE-7200 | Ethyl nonafluoroisobutyl ether | 3M, AGC | Heat transfer fluid, electronic cooling system, precision degreasing |
| HFE-7500 |
3-Ethoxyperfluoro(2-methylhexane) |
3M | Solvent carrier, coating remover, precision instrument cleaning |
| HFE-347 |
1,1,2,2-Tetrafluoroethyl 2,2,2-trifluoroethyl ether |
Daikin, JH | Electronic manufacturing, medical equipment sterilization |
Application areas
Application areas OF HFE Hydrofluoroether
Electronic manufacturing
Remove solder paste and flux residues, and clean PCB boards.
Replace HCFC and PFC to meet RoHS and REACH regulations.
Aerospace
Degreasing of precision parts, such as gyroscopes and fuel systems.
Medical equipment
Low-temperature cleaning and sterilization of endoscopes and surgical instruments.
Laboratory
Instrument maintenance, replacing highly toxic Freon.
Advantages vs. Traditional Solvents
| Comparison item | HFE | CFC-113 (phased out) | HCFC-141b |
| ODP (Ozone Depletion Potential) | 0 | 0.8 | 0.11 |
| GWP | ~350 | 6000 | 725 |
| Cleaning efficiency | High | High | Medium |
| Flammability | Non-flammable | Non-flammable | Flammable |
Basic information Of hFE-347
|
Product Name: |
1,1,2,2-Tetrafluoroethyl 2,2,2-trifluoroethyl ether |
|
CAS: |
406-78-0 |
|
MF: |
C4H3F7O |
|
MW: |
200.05 |
|
EINECS: |
609-858-6 |
|
Chemical Properties |
|
|
Boiling point |
56.2 °C |
|
density |
1.487 |
|
refractive index |
1.276 |
|
Specific Gravity |
1.487 |
|
CAS DataBase Reference |
406-78-0(CAS DataBase Reference) |
|
EPA Substance Registry System |
HFE-347pcf2 (406-78-0) |
|
Test items |
Specifications |
|
Appearance |
Clear colorless liquid |
|
Purity |
≥99.5% |
|
Water |
≤100ppm |
Why Choose Our HFE-347?
As a leading HFE manufacturer In China, we ensure:
High Purity (99.9%+) – Strict QC to prevent impurities.
Eco-Certified – Meets REACH, RoHS, and EPA SNAP guidelines.
Flexible Supply – Available in 1L lab bottles to bulk IBC totes.
Upgrade to a greener, safer solvent without sacrificing performance.
Contact our experts for technical datasheets, pricing, or custom formulations!
Our address
Room 1102, Unit C, Xinjing Center, No.25 Jiahe Road, Siming District, Xiamen, Fujan, China
Phone Number
+86-592-5803997
susan@xmjuda.com
