Xiamen Juda Chemical & Equipment Co., Ltd. is one of the leading manufacturers and suppliers of Pharmaceutical Grade HFA 152a: The Future of Medical Grade Propellants in China. If you are looking for Pharmaceutical Grade HFA 152a: The Future of Medical Grade Propellants, please be free to buy our quality products at competitive price from our factory. Contact us for quotation.
Pharmaceutical Grade HFA 152a: The Future of Medical Grade Propellants Tel:+86-592-5803997
HFA 152a (1,1-difluoroethane) represents the next generation of medical aerosol propellants, designed for the evolving regulatory and environmental landscape. As a leading low-GWP aerosol propellant-an alternative to HFA-134a and HFA-227ea-it offers pharmaceutical OEMs and formulation scientists a strategic pathway toward sustainable, future-compliant metered-dose inhaler (pMDI) platforms. With a Global Warming Potential (GWP) of 124 (more than 90% lower than legacy options), this medical-grade HFA 152a propellant directly addresses the economic and compliance pressures associated with global phase-down schedules, such as the Kigali Amendment.
Technical Specifications and Advantages of GWP
The key technical parameters of our pharmaceutical-grade HFA 152a medical propellant are detailed below.
| Property | Specification / Value | Notes / Comparison |
|---|---|---|
| Chemical name | 1,1-difluoroethane | - |
| Chemical formula | CH₃CHF₂ | - |
| Boiling point | -23.8 degrees | It provides high vapor pressure, suitable for aerosol products that require a higher spray rate. |
| Vapor pressure | High | Optimal for fast and consistent actuator performance. |
| Global Warming Potential (GWP) | 124 | 100-year timescale regarding CO₂. Significantly lower environmental GWP than alternatives. |
| GWP Comparison | HFA-134a: 1.430 HFA-227ea: 3220 HFA-152A: 124 |
Quantify the primary environmental performance advantage and the avoidance of carbon costs. |
| Regulatory status | Complies with the Kigali Amendment | Position the product to avoid future carbon tax costs (e.g., EU carbon tax ~€100/tonne of CO₂e). |
HFA-152a for Pharmaceutical MDI Formulation: A Technical and Regulatory Guide Tel:+86-592-5803997
This low-GWP aerosol propellant is more than just a drop-in replacement; it is a key component for the design of next-generation inhalers.
Formulation performance: With a boiling point of approximately -29.8°C, HFA-152A is more volatile than HFA-134a (-26.1°C), allowing for faster container evacuation and efficient dose delivery. This property is particularly advantageous for oral aerosols and specific pMDI formulations that require precise spray dynamics.
Regulatory pathway: Adopting HFA-152A is a proactive strategy for compliance with the Kigali Amendment. Its low-GWP profile safeguards your product portfolio against stringent HFC phase-out regulations and associated financial burdens, offering a clear, long-term alternative to HFA-134a and HFA-227ea.
B2B Procurement: From Development Samples to Bulk Supply Tel:+86-592-5803997
We are a specialized supplier of medical propellants, structured to meet the stringent requirements of the global pharmaceutical industry. We facilitate every stage, from early-stage R&D to commercial-scale manufacturing.
Scalable, cGMP-aligned packaging: Available in industry-standard, clean, disposable 22.2 lb (10.1 kg) cylinders for laboratory and pilot-scale work, scaling up to 926-ton cylinders and 22-ton ISO tank shipments for large-scale production, ensuring a secure and efficient supply chain.
Complete regulatory and quality documentation:As a trusted partner for the supply of OEM aerosol propellants, we provide comprehensive support for your regulatory submissions. Our products are backed by a Drug Master File (DMF) and manufactured under a certified quality management system (ISO, OHSAS), ensuring the high quality and batch-to-batch consistency required for pharmaceutical applications.
Technical Association:Our 20 years of experience in exporting fluorochemicals include dedicated R&D support. We collaborate on OEM/ODM projects, offering expertise in propellant behavior and compatibility to accelerate the transition and formulation optimization from HFA 134a to HFA 152a for MDIs.
Factory tour Tel:+86-592-5803997
Company Profile Tel:+86-592-5803997
Established in 1988, Xiamen Juda Chemical & Equipment Co., Ltd. was a subsidiary of the pioneering Chinese chemical manufacturer Juhua Group Corporation. Xiamen Juda has focused on the export of fluorinated chemicals since 2004. As one of the earliest exporters of refrigerants in China, we offer a comprehensive range of refrigerants and other fluorinated chemicals. Thirty-five years of development and quality certification have ensured the supply and quality service we provide to our long-term business partners worldwide across seven major product categories: refrigerant gas, medical aerosol propellants, cleaning agents, fire extinguishing agents, welding gas, cooling fluids, and fluoropolymers.
Our chemical products and packaging have achieved the following certifications: FDA DMF, UL, CE, DOT, KGS, ASME, ISO, and OHSAS.
Packaging Tel:+86-592-5803997
30 lb/13.6 kg disposable cylinder
926L Cylinder
22-Tonne ISO tank
Why Choose Us?
Years in the Industry
20 Years of Experience Exporting Fluorine-Based Chemicals and Equipment.
Quick Response
Any inquiry will be answered within 12 hours.
High Quality
Finished product inspection.
OEM/ODM available.
Feel free to contact us for more details about the product.
Frequently Asked Questions: Key Considerations for B2B Buyers
Q: Is the use of HFA-152a in pharmaceutical products accepted?
A: Yes, HFA-152a is a hydrofluoroalkane (HFA) propellant recognized and developed as an environmentally preferable alternative to CFCs and higher-GWP HFAs. It is suitable for medical aerosol products, including pMDI inhalers. Its adoption is supported by a regulatory strategy aligned with global environmental treaties.
Q: What specific documentation do you provide to support regulatory submissions?
A: We provide a comprehensive pharmaceutical data package, which may include access to our Drug Master File (DMF), a Certificate of Analysis for each batch, and detailed safety and handling data (SDS). This is part of our commitment to quality assurance and collaboration.
Q: Can you supply small quantities for formulation development and testing?
A: Absolutely. We support R&D efforts by supplying products in suitable packaging-such as smaller cylinders-to enable feasibility studies, compatibility testing, and actuator performance testing for pMDI inhaler propellants.
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